OMICS in Biomedical Sciences (Biomedical Sciences, UvA)
Coordinator: prof. dr. Antoine van Kampen and dr. Martijs Jonker.
Programme: Bachelor Biomedical Sciences (UvA); Second year.
Studie load: 12 EC (April / May)
First edition of the course was given in 2011
Omics technologies are increasingly being used in biomedical sciences. These are advanced laboratory techniques that are able to perform large-scale and detailed measurements at the molecular level. Thanks to these techniques, we are now able, for example, to map the complete human DNA sequence, or to measure the expression levels of all genes in a cell (about 20,000 for humans), or to measure large numbers of proteins or identify metabolites in the cell.
These new laboratory techniques have created many new possibilities. For example, by mapping the DNA sequences of patients, we can find out which mutations play a role in specific diseases. By mapping gene expression, we gain more insight into the functioning of biological networks and their changes in disease. Omics technologies provide new fundamental insights into the functioning of a cell in health and during disease, and also contribute to improved diagnosis and treatment of patients.
Unlike traditional laboratory techniques, omics technologies produce large amounts and/or complex data sets. The analysis of these datasets requires bioinformatics expertise. Bioinformatics is a scientific discipline in which statistics and informatics are used for the management, analysis and interpretation of omics data.
In this course you will also be introduced to systems biology. Systems biology aims to unravel and understand biological systems through the use of omics technologies, bioinformatics, and/or mathematical modelling. You will learn how omics, bioinformatics and systems biology contribute to biomedical research and diagnostics.