Annual ARCAID meeting 2021

On 25th October 2021 the first ull day ARCAID meeting, with all PhD students present, took place. The meeting was organized as a hybrid meeting with part of the audiance at the AMC and other part following the meeting from home via Zoom. All PhD students were at the AMC.

Dasha Balashova and Utkarsh Mahamune both gave a very good presentation about the status of their current research. Dasha showed results from the comparison of different methods for the determination of clonal families from repertoire sequencing experiments and, in particular, the impact on downstream analyses. Utkarsh explained how he aims to reconstruct gene regulatory networks from single cell RNAseq data.


9:00 – 9:05          Short Welcome and intro – Lisa van Baarsen, coordinating PI

Fellow presentations (5 minutes, 5 minutes discussion- focus)

Chair: Sander Tas/ Eva Phillipon

9:05 – 9:15           Initiate a pilot prevention trial in individuals at high risk for developing rheumatoid arthritis – Giulia Frazzei (ESR1)

9:15 – 9:25           Treat-to-target in systemic lupus erythematosus: design of a pilot study – Agner Parras (ESR2)

9:25 – 9:35           Gene expression in the HLA complex in autoimmune disease – Adrian Durotin (ESR3)

9:35 – 9:45          Clonal isotyping of the B cell response in autoimmunity – Armando Olivieri (ESR4)

9:45 – 9:55          (Short break for a breather..;-))

Chair: Adrian Durotin

9:55 – 10:05       Study the molecular and cellular features of human lymph node T cells during the earliest phases of systemic autoimmunity – Aoife O’Byrne (ESR5)

10:05 – 10:15     The role of B cells in ANCA-associated vasculitis – Ana Merino Vico (ESR7)

10:15 – 10:25     State-of-the-art in vivo PET-CT imaging of immune cell subsets in chronic inflammatory diseases and cancer – Eva Phillipon (ESR8)

10:25 – 10:35     Characterize the molecular pathways activated during the pre-clinical phase of spondyloarthritis – Ihsan Hammoura (ESR9)

10:35 – 11:00     Coffee/Tea break – award ceremony best video


Chair: Joep Grootjans/Sofia Liddle

11:00 – 11:10     The Implication of the Lymphatic System in the Pathogenesis of Inflammatory Bowel Disease and the Development of Immunogenicity against Therapeutic Monoclonal Antibodies- Dimitrios Nikolakis (ESR10)

11:10 – 11:20     Understanding auto-immune disorders through computational modelling – Utkarsh Mahamune (ESR11)

11:20- 11:30       Systematic evaluation of B cell clonal families inference approaches – Daria Balashova (ESR12)

11:30– 11:40      Understanding the etiology of IBD associated extraintestinal manifestations and cancer -Liddle Sofía Frigerio (ESR13)

11:40 – 11:50     Activated PI3Kδ in Systemic lupus Erythematosus (SLE) – Elham Sadat Mirfazeli (ESR14)

11:50 – 12:00     Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses – Chiara Geyer (ESR15)

12:00 – 13:00 Lunch

Chair: Jeroen den Dunnen/Chiara or Sona

13:00 – 13:10     Metabolic reprogramming of human myeloid immune cells during chronic inflammation – Sona Allaverdiyeva (ESR16)

13:10 – 13:20     Immune monitoring of macrophages in the development and progression of rheumatoid arthritis and immune checkpoint inhibitor-induced rheumatic manifestations – Aiarpi Ezdoglian (ESR17)

13:20 – 13:30     Molecular imaging of angiogenesis and therapeutic effects of anti-angiogenetic agents in rheumatoid arthritis – Khodadustvaskasi, Fatemeh (ESR18)

13:30 – 13:40     short break

13:40 – 13:50     Development of immune competent gut on chip model – Melis Asal (ESR19)

13:50 – 14:00     Development of a Lymph Node-on-chip – Andrew Morrison (ESR20)

14:00 – 14:30     The core facilities -imaging –Eric Reits

14:30 – 15:00     Coffee/Tea break

Chair: Conny/Fatemeh/Aiarpi

15:00-15:30        Possible techniques available within the core facilities of Genomics (CFG)- Elisabeth Lodder

15:30-16:00        Title: Picking up good ‘fibrations’ for the joints (via Teams)- Mario Zaiss, Erlangen, Germany

16:00-16:15        Results questionnaire – Laurian Jongejan, project manager

16:15-16:30        Concluding remarks Ronald van Vollenhoven, coordinating PI

16.30-17.30        Drinks and snacks to foster collaboration